Charité Universitätsmedizin Berlin

Neuroscience foundations; human tests using TMS and tDCS with a focus on impact on sleep and alertness; Ethics.

Charité Universitätsmedizin Berlin is one of the largest university hospitals in Europe with a strong focus on research. The research unit involved is based in the interdisciplinary sleep centre with physicians (internists, neurologists, psychiatrics, otorhinolaryngologists), theoretical scientists (physicist, and physiologist), and biomedical engineers. Ingo Fietze, MD, PhD is the Head of the Sleep Center, Martin Glos (medical engineer), Alexander Blau, MD, Dana Buck, MD, and Jan Giso Peter, MD are involved in clinical work and research. The sleep centre comprises neurology with two physicians which are Pascal Grosse, MD, PhD, and Farid Sali, MD. Their specific interest is epilepsy during sleep, movement disorders, and electrical stimulation during sleep. The main expertise of the unit is sleep physiology and sleep medicine in healthy subjects and patients. The unit has a long track of experience in testing new sensors, new devices and developing new algorithms. The unit had been involved in previous European research projects (SENSATION, DAPHNET, COST B26). The research unit has ample experience with TMS and electrophysiological signal processing through the physicians from the department of Neurology and the members of the team. Partner 2 will focus on foundations and M2B experiments with tCS and TMS. The sleep center can devote two beds with cardiorespiratory polysomnography and a synchronous multi-channel (32 channels) digital high resolution EEG recording over long time to this project. The latest long-time recordings with multi-channel recordings were performed in August 2007 as part of a 40 hour sleep deprivation experiment in a quasi-constant routine setting.

HIVE is supported by the European Commission under the Future and Emerging Technologies program.

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